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LUKE HUGHES, PHD TALKING BFR IN SPACE

This is one of our longer podcasts, but we cover a ton of ground here when it comes to space travel and the muscle, bone, and nervous system responses. Ultimately we’re curious how BFR might provide some solutions both for terrestrial life as well as for space travel and Dr. Luke Hughes helps us understand how BFR might fit into the picture. We hope you enjoy!!

Opening backing track used under the Creative Commons license linked below. Sound bite for the backing track produced by Lauren Ponder on Freesound: freesound.org/people/LaurenPonder/

Creative Commons license: creativecommons.org/licenses/by-nc/4.0/legalcode

If you have questions or a topic that you want to hear about, you can submit the topic or question through our website. If your question/topic gets selected, you can receive a free ORS shirt. To submit a question to be read on our podcast email: info@owensrecoveryscience.com and include #podcast in the subject line.

ALEX FRANZ, MD

In this newest episode Johnny and Kyle talk with Dr. Alex Franz from the Department of Orthopedics and Trauma Surgery at the University Hospital of Bonn. We discuss Dr. Franz's extensive research in blood flow restriction exercise and how he's using that path to solve big problems in medicine! This conversation is pretty epic! You're sure to enjoy. Below you'll find the papers of his we discussed.

Franz, A., Queitsch, F. P., Behringer, M., Mayer, C., Krauspe, R., & Zilkens, C. (2018). Blood flow restriction training as a prehabilitation concept in total knee arthroplasty: A narrative review about current preoperative interventions and the potential impact of BFR. Medical Hypotheses, 110, 53–59.

Franz, A., Behringer, M., Nosaka, K., Buhren, B. A., Schrumpf, H., Mayer, C., Zilkens, C., & Schumann, M. (2017). Mechanisms underpinning protection against eccentric exercise-induced muscle damage by ischemic preconditioning. Medical Hypotheses, 98, 21–27.

Franz, A., Behringer, M., Harmsen, J.-F., Mayer, C., Krauspe, R., Zilkens, C., & Schumann, M. (2018). Ischemic Preconditioning Blunts Muscle Damage Responses Induced by Eccentric Exercise. Medicine and Science in Sports and Exercise, 50(1), 109–115.

Franz, A., Berndt, F., Raabe, J., Harmsen, J.-F., & Behringer, M. (2020). Invasive Assessment of Hemodynamic, Metabolic and Ionic Consequences During Blood Flow Restriction Training. Frontiers in Physiology. doi.org/10.3389/fphys.2020.617668

Alexander Franz, Sanghyeon Ji, Bernd Bittersohl, Christoph Zilkens, MichaelBehringer. (n.d.). Impact of a Six-Week Prehabilitation with Blood-Flow Restriction Training on Pre- and Postoperative Skeletal Muscle Mass and Strength in Patients Receiving Primary Total Knee Arthroplasty.

WHEN BFR DOESN'T WORK

In this episode Johnny and the fellas discuss 4 papers where BFR did not work! What?!? How can that be???

Well...gotta listen to find out! Check out the full podcast here. 

We begin by discussing briefly how hard research in medicine is...
Here's a reference:
Howick, J., Koletsi, D., Ioannidis, J. P. A., Madigan, C., Pandis, N., Loef, M., Walach, H., Sauer, S., Kleijnen, J., Seehra, J., Johnson, T., & Schmidt, S. (2022). Most healthcare interventions tested in Cochrane Reviews are not effective according to high quality evidence: a systematic review and meta-analysis. Journal of Clinical Epidemiology, 148, 160–169.

And here's a podcast discussing the paper:
ptinquest.com/episode-250-most-h…-quality-evidence/

Here's the paper Zac describes:
Tramer, J. S., Khalil, L. S., Jildeh, T. R., Abbas, M. J., McGee, A., Lau, M. J., Moutzouros, V., & Okoroha, K. R. (2022). Blood Flow Restriction Therapy For Two Weeks Prior to Anterior Cruciate Ligament Reconstruction Did Not Impact Quadriceps Strength Compared to Standard Therapy. Arthroscopy: The Journal of Arthroscopic & Related Surgery: Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association. doi.org/10.1016/j.arthro.2022.06.027

Here's the paper Kyle describes:
Iversen, E., Røstad, V., & Larmo, A. (2016). Intermittent blood flow restriction does not reduce atrophy following anterior cruciate ligament reconstruction. Journal of Sport and Health Science, 5(1), 115–118.

Here's the paper Johnny describes:
Curran, M. T., Bedi, A., Mendias, C. L., Wojtys, E. M., Kujawa, M. V., & Palmieri-Smith, R. M. (2020). Blood Flow Restriction Training Applied With High-Intensity Exercise Does Not Improve Quadriceps Muscle Function After Anterior Cruciate Ligament Reconstruction: A Randomized Controlled Trial. The American Journal of Sports Medicine, 48(4), 825–837.

And here's the paper Ben describes:
Brumitt, J., Hutchison, M. K., Kang, D., Klemmer, Z., Stroud, M., Cheng, E., Cayanan, N. P., & Shishido, S. (2020). Blood Flow Restriction Training for the Rotator Cuff: A Randomized Controlled Trial. International Journal of Sports Physiology and Performance, 1–6.

If you have questions or a topic that you want to hear about, you can submit the topic or question through our website. If your question/topic gets selected, you can receive a free ORS shirt. To submit a question to be read on our podcast email: info@owensrecoveryscience.com and include #podcast in the subject line.

Intro soundbite: Trick or Treat (instrumental) by RYYZN @ryyzn

Creative Commons — Attribution 3.0 Unported — CC BY 3.0
Free Download / Stream: bit.ly/l_trick-or-treat
Music promoted by Audio Library youtu.be/uNPXJ9CDzbc

BFR AND CONCUSSION?
MEMORIAL DAY 2022 - EPISODE 1

The first of two Memorial Day podcasts this year. Begin this podcast at 1:33PM local to observe The National Moment of Remembrance at 3PM local.

In this podcast Major General Daniel Walrath (ret) discusses his service, his injury, and his recovery with Johnny.

He concludes by memorializing the 4 people killed in the attack on his group in Afghanistan.

Listen to the full podcast here.

In Memoriam:

Command Sergeant Major Kevin Griffin
Major Tommy Kennedy
Major Walter ‘David’ Gray
US Citizen Mr. Ragaei Abdelfattah of the US Agency for International Development

MEMORIAL DAY 2022 - EPISODE 2

In our second installment of our special Memorial Day releases we have our instructor Zac Dunkle talking with fellow Marine, Gunnery Sergeant Tom Schmidt. They discuss:

Tom's time in the service

Its impact on his life

The Rush of War - why some guys keep going back

Task Force 8211 Fox Company

Listen to the full podcast here.

In Memoriam:
Team Chief Master Sergeant Eden Pearl
Nick Roush US ARMY Phyops (physiological operations)
American citizen and interpreter Ya Hamid Ali Jimshi

DISCUSSING BFR IN NEUROLOGICAL POPULATIONS AND ADOLESCENTS

In this episode the guys discuss two recent papers that build off of previous podcasts. The first article discussed is the use of BFR in Adolescents after ACLR. We previously chatted with the authors of this paper on our episode from June 23, 2020 titled "BFR in Kids!?!"

The second paper discussed is a recent survey that was published looking into the use of BFR in persons with neurological conditions. We previously chatted with the primary author of this paper Mark Mañago, PT, DPT, PhD, NCS on November 18, 2020

Check out the full discussion here

If you have questions or a topic that you want to hear about, you can submit the topic or question through info@owensrecoveryscience.com with the subject line #podcast. If your question/topic gets selected, you can receive a free ORS shirt. 

References:

Prue, J., Roman, D. P., Giampetruzzi, N. G., Fredericks, A., Lolic, A., Crepeau, A., Pace, J. L., & Weaver, A. P. (2022). Side effects and patient tolerance with the use of blood flow restriction training after ACL reconstruction in adolescents: A pilot study. International Journal of Sports Physical Therapy. https://doi.org/10.26603/001c.32479

Mañago, M. M., Kimbrell, K., Hager, E. R., Dwight, H., Owens, J., & Bade, M. (2022). Clinical use of blood flow restriction in people with neurologic conditions: a cross-sectional survey. Journal of Physical Therapy Science, 34(4), 275–283.

Intro sound bite from: Trick or Treat (instrumental) by RYYZN @ryyzn
Creative Commons — Attribution 3.0 Unported — CC BY 3.0
Free Download / Stream: bit.ly/l_trick-or-treat
Music promoted by Audio Library youtu.be/uNPXJ9CDzbc

BROACHING THE SUBJECT OF PBFR WITH A SURGEON

Our team discusses the ever growing popularity of blood occlusion training in clinical settings including recent publications from Orthopedic leaders and its overall safety. We also interview Maj Travis Burns, MD, Chief of Sports Medicine at San Antonio Military Medical Center, one of the early surgeons to embrace BFR training post-operatively in the US. Lastly, we answer questions from our listeners. Check out the full podcast here

Journal of Arthroscopy Dr Brian Day commentary https://www.arthroscopyjournal.org/article/S0749-8063(18)30487-0/fulltext 

Journal of Arthroscopy Dr Robert LaPrade commentary https://www.arthroscopyjournal.org/article/S0749-8063(18)30475-4/fulltext 

Techniques in Orthopedics Special BFR Edition journals.lww.com/techortho/Fullte…rrent_and.1.aspx 

BFR for Pre-hab total joint replacements www.sciencedirect.com/science/articl…882?via%3Dihub 

BFR case series post-op weakness DOD insights.ovid.com/crossref?an=0014…-201804000-00006 

BFR case series Achilles Rupture DOD www.jfas.org/article/S1067-2516…7)30645-2/fulltext 

BFR after knee arthroscopy DOD insights.ovid.com/crossref?an=0004…-201705000-00002 

If you have questions or a topic that you want to hear about, you can submit the topic or question through our website. If your question/topic gets selected, you can receive a free ORS shirt. To submit a question to be read on our podcast go to our website: OwensRecoveryScience.com -Contact -In the body of email put #Podcast Qualifications for a chance to win a free ORS T-shirt: Your question is read on our podcast and You are a subscriber on YouTube/Podcast

BFR AND VTE

In this episode Johnny and the guys tackle the complicated decision making process involved in choosing whether or not to use BFR when considering VTE risk factors. Below we’ve included the notes with bibliography that we worked from so that you can follow along if you like. We hope you enjoy it!! Check out the full podcast here

If you have questions or a topic that you want to hear about, you can submit the topic or question through our website. If your question/topic gets selected, you can receive a free ORS shirt. To submit a question to be read on our podcast email: info@owensrecoveryscience.com and include #podcast in the subject line 

Caprini risk assessment - venousdisease.com/caprini-dvt-risk-assessment-app/ 

References: 

Dragoman MV, Tepper NK, Fu R, Curtis KM, Chou R, Gaffield ME. A systematic review and meta-analysis of venous thrombosis risk among users of combined oral contraception. Int J Gynaecol Obstet. 2018;141(3):287-294. 

Practice Committee of the American Society for Reproductive Medicine. Electronic address: ASRM@asrm.org, 

Practice Committee of the American Society for Reproductive Medicine. Combined hormonal contraception and the risk of venous thromboembolism: a guideline. Fertil Steril. 2017;107(1):43-51. 

Heit JA, Kobbervig CE, James AH, Petterson TM, Bailey KR, Melton LJ 3rd. Trends in the incidence of venous thromboembolism during pregnancy or postpartum: a 30-year population-based study. Ann Intern Med. 2005;143(10):697-706. 

Sweetland S, Green J, Liu B, et al. Duration and magnitude of the postoperative risk of venous thromboembolism in middle aged women: prospective cohort study. BMJ. 2009;339:b4583. 

Roberts LN, Porter G, Barker RD, et al. Comprehensive VTE prevention program incorporating mandatory risk assessment reduces the incidence of hospital-associated thrombosis. Chest. 2013;144(4):1276-1281. 

Shaw DM. Factor V Leiden- An Overview. Clin Lab Sci. 2006;19(4):218-221. Adams M, Fell J, Williams A. Exercise causing thrombosis. Phys Sportsmed. 2009;37(4):124-130. 

Hilberg T, Jeschke D, Gabriel HHW. Hereditary thrombophilia in elite athletes. Med Sci Sports Exerc. 2002;34(2):218-221. 

Martinelli I, Taioli E, Battaglioli T, et al. Risk of venous thromboembolism after air travel: interaction with thrombophilia and oral contraceptives. Arch Intern Med. 2003;163(22):2771-2774. 

Naess IA, Christiansen SC, Romundstad P, Cannegieter SC, Rosendaal FR, Hammerstrøm J. Incidence and mortality of venous thrombosis: a population-based study. J Thromb Haemost. 2007;5(4):692-699. 

Ocak G, Vossen CY, Verduijn M, et al. Risk of venous thrombosis in patients with major illnesses: results from the MEGA study: Major illnesses and venous thrombosis. J Thromb Haemost. 2013;11(1):116-123. 

Furie B, Furie BC. Mechanisms of thrombus formation. N Engl J Med. 2008;359(9):938-949. 

Dahlbäck B. Advances in Understanding Mechanisms of Thrombophilic Disorders. Hamostaseologie. 2020;40(1):12-21. 

Kumar DR, Hanlin E, Glurich I, Mazza JJ, Yale SH. Virchow’s contribution to the understanding of thrombosis and cellular biology. Clin Med Res. 2010;8(3-4):168-172. 

Sharma P. Paget-Schroetter syndrome after a dental procedure in a patient with factor V Leiden (R506Q) heterozygosity. Blood Coagul Fibrinolysis. 2017;28(3):269-271. slusher2010.pdf. 

Donahue BS. Factor V Leiden and perioperative risk. Anesth Analg. 2004;98(6):1623-1634, table of contents. 

Makris M. Factor V Leiden: to test or not to test, that is the debate. Blood Transfus. 2012;10(3):255-256. 

van Stralen KJ, Rosendaal FR, Doggen CJM. Minor injuries as a risk factor for venous thrombosis. Arch Intern Med. 2008;168(1):21-26. Factor V (5) Leiden Thrombophilia. https://www.ncbi.nlm.nih.gov/books/NBK1368/pdf/Bookshelf_NBK1368.pdf. 

Bond CW, Hackney KJ, Brown SL, Noonan BC. Blood Flow Restriction Resistance Exercise as a Rehabilitation Modality Following Orthopaedic Surgery: A Review of Venous Thromboembolism Risk. J Orthop Sports Phys Ther. 2019;49(1):17-27. 

Jarrett PM, Ritchie IK, Albadran L, Glen SK, Bridges AB, Ely M. Do thigh tourniquets contribute to the formation of intra-operative venous emboli? Acta Orthop Belg. 2004;70(3):253-259. 

Noto T, Hashimoto G, Takagi T, et al. Paget-Schroetter Syndrome Resulting from Thoracic Outlet Syndrome and KAATSU Training. Intern Med. 2017;56(19):2595-2601.

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